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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VARS
All Species:
18.48
Human Site:
S1225
Identified Species:
25.42
UniProt:
P26640
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P26640
NP_006286.1
1264
140476
S1225
L
R
E
R
R
A
A
S
G
Y
P
V
K
V
P
Chimpanzee
Pan troglodytes
XP_001160008
1264
140384
S1225
L
Q
E
R
R
A
A
S
G
Y
P
V
K
V
P
Rhesus Macaque
Macaca mulatta
Q5TM74
1064
118624
S1040
S
S
L
Q
L
E
L
S
K
L
D
K
A
A
S
Dog
Lupus familis
XP_538837
1256
139671
S1217
L
R
E
R
R
A
A
S
G
Y
P
V
K
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1Q9
1263
140197
S1224
L
Q
E
R
R
A
A
S
S
Y
S
A
K
V
P
Rat
Rattus norvegicus
Q04462
1264
140350
S1225
L
Q
E
R
R
A
A
S
G
Y
S
A
K
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520676
985
109386
A961
E
T
T
E
T
R
A
A
E
A
V
R
Q
T
L
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001088439
1243
140617
A1204
L
R
E
R
M
G
S
A
D
Y
R
S
K
V
P
Zebra Danio
Brachydanio rerio
XP_682807
1111
123867
N1072
M
K
E
K
M
T
K
N
D
Y
K
E
K
V
P
Tiger Blowfish
Takifugu rubipres
P49696
1217
138200
G1178
L
S
E
K
I
S
K
G
D
Y
K
E
K
V
P
Fruit Fly
Dros. melanogaster
NP_524838
1049
118236
N1025
P
A
E
V
Q
E
A
N
E
T
K
L
C
E
S
Honey Bee
Apis mellifera
XP_395202
1043
121057
N1019
P
L
D
V
Q
N
S
N
M
E
K
L
T
N
N
Nematode Worm
Caenorhab. elegans
Q9U1Q4
1050
118902
Q1026
V
D
I
R
A
L
D
Q
E
K
K
A
T
L
E
Sea Urchin
Strong. purpuratus
XP_001200958
1119
126755
S1092
V
P
E
R
I
Q
L
S
N
K
I
K
F
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P93736
1108
125908
I1084
N
A
N
K
L
A
K
I
L
Q
E
F
D
F
F
Baker's Yeast
Sacchar. cerevisiae
P07806
1104
125751
N1078
N
T
Q
A
K
E
A
N
K
S
K
L
D
N
T
Red Bread Mold
Neurospora crassa
P28350
1093
123334
Q1069
A
V
Q
E
S
E
K
Q
K
L
A
D
A
Q
A
Conservation
Percent
Protein Identity:
100
99.5
43.4
92.8
N.A.
93.4
93.4
N.A.
63
N.A.
65.3
45
63.8
50.9
49.1
44.9
44.4
Protein Similarity:
100
99.8
56
95.6
N.A.
96.4
96.3
N.A.
69.8
N.A.
78
58.8
76.8
63.1
63.4
59.5
59.6
P-Site Identity:
100
93.3
6.6
100
N.A.
73.3
80
N.A.
6.6
N.A.
53.3
33.3
40
13.3
0
6.6
20
P-Site Similarity:
100
100
13.3
100
N.A.
80
86.6
N.A.
20
N.A.
66.6
60
53.3
33.3
33.3
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
41.6
42.6
40.3
Protein Similarity:
N.A.
N.A.
N.A.
58.3
60.1
56
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
33.3
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
12
0
6
6
36
48
12
0
6
6
18
12
6
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
6
0
0
% C
% Asp:
0
6
6
0
0
0
6
0
18
0
6
6
12
0
0
% D
% Glu:
6
0
59
12
0
24
0
0
18
6
6
12
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
6
6
6
6
% F
% Gly:
0
0
0
0
0
6
0
6
24
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
6
0
12
0
0
6
0
0
6
0
0
0
0
% I
% Lys:
0
6
0
18
6
0
24
0
18
12
36
12
48
0
0
% K
% Leu:
42
6
6
0
12
6
12
0
6
12
0
18
0
6
6
% L
% Met:
6
0
0
0
12
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
12
0
6
0
0
6
0
24
6
0
0
0
0
12
6
% N
% Pro:
12
6
0
0
0
0
0
0
0
0
18
0
0
0
48
% P
% Gln:
0
18
12
6
12
6
0
12
0
6
0
0
6
6
0
% Q
% Arg:
0
18
0
48
30
6
0
0
0
0
6
6
0
0
0
% R
% Ser:
6
12
0
0
6
6
12
42
6
6
12
6
0
0
12
% S
% Thr:
0
12
6
0
6
6
0
0
0
6
0
0
12
6
6
% T
% Val:
12
6
0
12
0
0
0
0
0
0
6
18
0
48
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
48
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _